Introduction to the TOFMS Course

Time-of-Flight and Distance-of-Flight Mass Spectrometry

The use of time-of-flight mass spectrometry (TOFMS) with atomic ionization sources offers unique capabilities and formidable advantages, many of which have yet to be fully exploited. Here, plasma-source TOFMS is critically examined, including basic theoretical concepts, critical instrumental components, commercial solutions, and aspects of analytical performance. Applications from biology, clinical chemistry, geology, materials science that highlight the unique attributes of plasma-source TOFMS are reviewed, with particular emphasis on the use of transient sample introduction sources such as chromatography, single particle analysis, or laser-ablation. Finally, future developments are considered, including distance-of-flight mass spectrometry and aspects of single-cell elemental analysis.

This course is deemed suitable for those wishing a basic grounding in TOFMS concepts and instrumentation, and those wishing details of plasma-source TOFMS.

Course presenter


Prof Gary M. Hieftje

Indiana University - Department of Chemistry

Gary M. Hieftje is Distinguished Professor and Mann Chair of Chemistry at Indiana University in Bloomington, Indiana. His research interests include the investigation of basic mechanisms in atomic emission, absorption, fluorescence and mass spectrometric analysis, and the development of instrumentation and techniques for atomic, molecular, and biomolecular methods of analysis. He is interested also in the on-line computer control of chemical instrumentation and experiments, the use of time-resolved luminescence processes for analysis, the application of information theory to analytical chemistry, analytical mass spectrometry, near-infrared reflectance analysis, metallomics, and the use of stochastic processes to extract basic and kinetic chemical information.

He has won numerous awards in the fields of analytical chemistry, chemical instrumentation, and spectroscopy, has held major offices in several scientific societies, has delivered many named lectures, and has served on the editorial boards of many major journals. He is the author of over 600 publications, 13 books, 20 chapters, and 22 patents. To date, 70 students have received doctorates under his direction; many others have received M.S. degrees, and scores of undergraduates and visiting scientists have performed research in his laboratories.


Registration closes on Monday 23 July 2018.

Delegate Cost: R 1499.00

Full-time Student Cost: R 1150.00

Cost includes VAT, course handouts, light lunch, tea and coffee

Date:     Thursady 26 July 2018

Time:     10:00 - 17:00

Venue:   Casa Toscana Guesthouse, Pretoria


Map to the course venue

Casa Toscana Guesthouse, Pretoria

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